Nutritional Fundamentals for Health

 
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New and Improved Curcumin SAP

Curcumin from the vibrant yellow spice Turmeric (Curcuma longa L.) has been extensively used for its vast range of health benefits towards colon health, rheumatoid arthritis, prostate health, immunomodulation, neuroprotection and cardiovascular health. However, curcumin has poor bioavailability owing to its low water solubility and rapid metabolism and systemic elimination upon oral consumption. NFH now offers a new and improved evidence‑based Curcumin SAP with added piperine that helps improve bioavailability and efficacy of curcumin for optimal health.

CURCUMIN-PIPERINE SYNERGY
Combination of curcumin/curcuminoids and piperine from Piper nigrum extract has been clinically shown to increase the bioavailability of curcuminoids by almost 20 folds (1). Researchers reported the specific increase in bioavailability of curcumin itself and not its phase II metabolites. The rapid biotransformation of curcumin via phase II metabolism lowers the bioactivity of curcumin. Piperine is known to inhibit the formation of phase II metabolites by inhibiting hepatic and intestinal glucuronidation (2). Simultaneous consumption of 5 mg of piperine along with Curcuminoids has shown to increase the bioavailability of curcumin.[2] In addition, the thermogenesis activity of piperine facilitates sustenance of the metabolic process and enables better absorption of nutrients in the intestine.[1, 2] 

NFH Curcumin SAP is tested for curcumin I, demethoxycurcumin, and bisdemethoxycurcumin.

References: 
  1. Shoba G, Joy D, Joseph T, Majeed M, Rajendran R, Srinivas PS. Planta Med. 1998, 64 (4), 353-6. 
  2. Singh J, Dubey RK, Atal CK. J. Pharmacol. Exp. Ther. 1986, 236 (2), 488-93.